Cat Polycystic Kidney Disease (PKD) DNA Test
When you know your cat is affected, you can get help sooner.
How do I know if my Cat has the Mutation for PKD?
The only way to know for sure if your velvet-pawed pet is affected by the mutation for PKD is through DNA testing. Although there is no cure for affected cats, symptoms can be managed as directed by your veterinarian. This disease is most often seen in Persians. Not sure if this test is right for your cat? Contact us for a free consultation.
Two Options for Cat DNA Collection
- Want us to send you a kit? Choose Mail Collection Kit at checkout
- Don’t want to wait for a kit? Choose DIY Collection Kit at checkout
Name: Polycystic Kidney Disease (PKD)
DNA Samples: Collected at Home Using Cheek Swabs
Cost: $48 + S&H per Cat
Results: Within 10 Business Days after Receipt of Samples
PKD DNA Testing for Cats
Polycystic Kidney Disease (PKD) is an inherited autosomal dominant disorder characterized by the formation of cysts on the kidneys, PKD could lead to eventual renal failure and possible death. The PKD DNA test is available for the following cats breeds: Persians, Himalayans, Exotics, and crosses of these three.
PKD is dominant,therefore, heterozygotes (those possessing one copy of the mutation) will likely be clinically affected. When bred to genotypically-normal cats, heterozygotes are still likely to produce clinically affected offspring 50% of the time.
Your PKD DNA-test kit includes:
- Sterile DNA-collection swabs
- Complete instructions
- Postage-paid return envelope (if mailed in the U.S.)
You can also use a DIY kit to collect samples, if you prefer.
Once testing is complete, we email a detailed DNA report showing the cat’s genotype for PKD.
The 3 possible genotypes include:
- NN: 2 copies of the normal allele
- NP Heterozygote: 1 normal copy and 1 copy of the PKD mutation
- PP: 2 copies of the PKD mutation
Polycystic Kidney Disease Inheritance
The following table shows the expected distribution of progeny genotypes based on a mating where both parents have known genotypes.
N = Normal Allele
P = PKD Mutation
NN = 2 normal copies of the gene|
NP = 1 Normal copy, 1 copy of PKD mutation
PP = 2 copies of the PKD mutation