How do I Know if my Dog Carries the Mutation for DM?

Degenerative Myelopathy (DM) is a devastating degenerative disease of the spinal cord that can progress rapidly and cause weakness in the hind limbs—and eventually paraplegia—in affected dogs.

Our DM DNA test, which uses the SOD1-A marker, is available for all dog breeds.

Please note: We do not test for the SOD1-B marker found in Bernese Mountain Dogs. It’s been known for several years that the Bernese have this additional marker/risk factor that is generally restricted to the breed. This is not to say that this marker is the sole cause of DM in that breed or that the SOD1-A mutation is irrelevant as a risk factor in the breed.

Our DNA test for DM in dogs gives breeders an accurate, convenient, and affordable tool to help them avoid producing DM-affected offspring and significantly reduce the gene frequency in future generations.

DNA results are emailed within 5 business days, once all samples are received at the laboratory.

Not sure if you need this test? Type your breed into the box above or contact us for a free consultation.

Your Degenerative Myelopathy (DM) DNA-test kit includes:

• Sterile DNA-collection swabs
• Complete instructions

Postage-paid return envelope (if mailed in the U.S.)

Understanding Results

There are 3 possible genotypes reported for Degenerative Myelopathy (DM):

• CLEAR: those having 2 copies of the normal allele and appear to be normal
• CARRIER: those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal

AFFECTED: those having 2 copies of the mutation are likely to show clinical signs