Cystinuria DNA Test

How do I Know if my Dog Carries the Mutation for Cystinuria?

Cystinuria Disease is an inherited autosomal recessive disorder that is characterized by the formation of cystine stones in the kidney, ureter, and bladder. In an affected dog, the kidneys do not adequately reabsorb certain amino acids during the filtering process, thus resulting in excess excretion of these monomers. The amino acids may then precipitate and form crystals or stones in the kidneys, ureters, or bladder, which can be very painful for the dog

Our DNA test for Cystinuria gives Labrador and Newfoundland breeders an accurate, convenient, and affordable tool to help them avoid producing CNM-affected offspring and significantly reduce the gene frequency in future generations. This test is validated for these two breeds only.

DNA results are emailed within 5 business days, once all samples are received at the laboratory.

Not sure if you need this test? Type your breed into the box above or contact us for a free consultation.

Your Cystinuria DNA-test kit includes:

• Sterile DNA-collection swabs
• Complete instructions

Postage-paid return envelope (if mailed in the U.S.)

Understanding Results

There are 3 possible genotypes reported for Cystinuria Disease:

• CLEAR: those having 2 copies of the normal allele and appear to be normal
• CARRIER: those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal
• AFFECTED: those having 2 copies of the mutation and are at risk of developing stones